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1-(6-chloropyridazin-3-yl)-4-methyl-1,4-diazepane synthesis

3synthesis methods
-

Yield:223796-04-1 28%

Reaction Conditions:

with 40percent HCHO at 110; for 2.5 h;

References:

Toma, Lucio;Quadrelli, Paolo;Bunnelle, William H.;Anderson, David J.;Meyer, Michael D.;Cignarella, Giorgio;Gelain, Arianna;Barlocco, Daniela [Journal of Medicinal Chemistry,2002,vol. 45,# 18,p. 4011 - 4017]