1-(6-METHOXY-2-NAPHTHYL)ETHAN-1-ONE OXIME synthesis
- Product Name:1-(6-METHOXY-2-NAPHTHYL)ETHAN-1-ONE OXIME
- CAS Number:3893-38-7
- Molecular formula:C13H13NO2
- Molecular Weight:215.25
3900-45-6
382 suppliers
$10.00/10g
3893-38-7
14 suppliers
inquiry
Yield:3893-38-7 93%
Reaction Conditions:
with hydroxylamine hydrochloride in methanol at 50; for 4 h;Inert atmosphere;
Steps:
1 Step 1: synthesis of 1-(6-methoxynaphthalen-2-yl)ethanone oxime (A4-2)
1-(6-methoxynaphthalen-2-yl)ethanone (600 mg, 3.00 mmol, 1.0 eq), hydroxylamine hydrochloride (625 mg, 8.99 mmol, 3.0 eq) and methanol (15 mL) were sequentially added to a dry 100 mL one-neck flask, and stirred for 4 hours at 50°C under nitrogen atmosphere. After the product was detected by TLC, the reaction solution was poured into ice water (200 mL), filtered, and dried to give a product 1-(6-methoxynaphthalen-2-yl)ethanone oxime (600 mg, white solid), yield 93%.
References:
EP3434674,2019,A1 Location in patent:Paragraph 0152; 0153
93-04-9
457 suppliers
$13.00/25g
3893-38-7
14 suppliers
inquiry