1-acetoxycyclopropanecarboxylic acid synthesis

3synthesis methods

Product Name:1-acetoxycyclopropanecarboxylic acid
CAS Number:123056-60-0
Molecular formula:C6H8O4
Molecular Weight:144.13

17994-25-1 Synthesis

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108-24-7
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123056-60-0
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Yield:123056-60-0 796 mg

Reaction Conditions:

for 2 h;Reflux;

Steps:

21.A (A)
1-Acetoxycyclopropanecarboxylic acid

(A)
1-Acetoxycyclopropanecarboxylic acid
A mixture of 1-hydroxycyclopropanecarboxylic acid (600 mg) and acetic anhydride (2 mL) was heated at reflux for 2 hours.
The reaction mixture was diluted with water (5 mL) and then concentrated under reduced pressure.
The residue was diluted with toluene and then concentrated under reduced pressure to obtain the title compound (796 mg).
¹H NMR (300 MHz, CDCl₃) δ 1.17-1.36 (2H, m), 1.51-1.70 (2H, m), 2.10 (3H, s), 3.33-6.83 (1H, m).

References:

EP3133075,2017,A1 Location in patent:Paragraph 0329

17994-25-1 Synthesis

17994-25-1
170 suppliers
$7.00/100mg

75-36-5 Synthesis