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139026-44-1

1-ADAMANTYL(PHENYL)METHANAMINE synthesis

2synthesis methods
-

Yield:139026-44-1 65%

Reaction Conditions:

Stage #1: bromobenzenewith magnesium in diethyl ether;
Stage #2: 1-adamantanecarbonitrile in tetrahydrofuran; for 8 h;
Stage #3: with lithium aluminium tetrahydride in tetrahydrofuran; for 40 h;Heating;Further stages.;

References:

Averin, Alexei D.;Ranyuk, Elena R.;Golub, Svetlana L.;Buryak, Alexei K.;Savelyev, Evgenii N.;Orlinson, Boris S.;Novakov, Ivan A.;Beletskaya, Irina P. [Synthesis,2007,# 14,p. 2215 - 2221]