1-(Aminooxy)-2-propene synthesis
- Product Name:1-(Aminooxy)-2-propene
- CAS Number:6542-54-7
- Molecular formula:C3H7NO
- Molecular Weight:73.09
42832-42-8
0 suppliers
inquiry
6542-54-7
4 suppliers
inquiry
Yield:-
Reaction Conditions:
with hydrogenchloride in ethanol;water at 50; for 5 h;
Steps:
3.2.2. General Procedure for Synthesis of O-substituted hydroxylamines 3d-3j
General procedure: The water (5 mL) mixing hydroxylamine hydrochloride (0.10 mol), ethyl acetate(0.18 mol) and 28% sodium hydroxide aqueous solution (25 mL) were stirred at 0 C.The resultant mixture was then stirred at room temperature for 1 h. After that, halogenated hydrocarbon (0.11 mol) was dropwise added and the reaction was stirred at 60 C for further 6 h. Subsequently, the reaction mixture was extracted with petroleum ether and ethyl acetate. The organic layer was combined and dried by anhydrous sodium sulfate,then the solvent was removed under reduced pressure and oily product was obtained.The obtained oily product was dissolved in ethyl alcohol, and 36% aqueous hydrochloric acid was added to the solution. The mixture was stirred at 50 C for 4 h. Finally, the reactionbwas neutralized to pH 7.0 by saturated sodium bicarbonate aqueous solution, and thenextracted with dichloromethane. The extracts were dried over anhydrous sodium sulfate,and concentrated under vacuum to obtain the title compounds 3d-3j
References:
Dai, Peng;Jiao, Jian;Wang, Qing-Qing;Zhang, Shu-Guang;Zhang, Wei-Hua [Molecules,2021,vol. 26,# 2]
39020-79-6
61 suppliers
$36.00/5g
6542-54-7
4 suppliers
inquiry
61807-43-0
2 suppliers
inquiry
6542-54-7
4 suppliers
inquiry
42832-36-0
0 suppliers
inquiry
6542-54-7
4 suppliers
inquiry