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1-Benzyl-5-hydroxypiperidin-2-one synthesis

4synthesis methods
24211-54-9 Synthesis
(S)-5-HYDROXY-PIPERIDIN-2-ONE

24211-54-9
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1-Benzyl-5-hydroxypiperidin-2-one

87179-80-4
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-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: imidazole; DMAP / dimethylformamide / 40 °C
2: NaH / dimethylformamide
3: HCl / methanol

References:

Fan, Gao-Jun;Wang, Zhongyi;Wee, Andrew G. H. [Chemical Communications,2006,# 35,p. 3732 - 3734]