![](/CAS/GIF/16689-35-3.gif)
1-Boc-2-isopropylhydrazine synthesis
- Product Name:1-Boc-2-isopropylhydrazine
- CAS Number:16689-35-3
- Molecular formula:C8H18N2O2
- Molecular Weight:174.24
![tert-Butyl carbazate](/CAS/GIF/870-46-2.gif)
870-46-2
533 suppliers
$5.00/10g
![Acetone](/CAS/GIF/67-64-1.gif)
67-64-1
6 suppliers
$17.30/10ml
![1-Boc-2-isopropylhydrazine](/CAS/GIF/16689-35-3.gif)
16689-35-3
110 suppliers
$11.00/250mg
Yield: 95.6%
Reaction Conditions:
with sodium tris(acetoxy)borohydride;magnesium sulfate;acetic acid in dichloromethane at 20;
Steps:
18.1 Step 1: Synthesis of tert-butyl 2-isopropylhydrazine-1-carboxylic acid
Tert-butyl hydrazinoformate (20.0g, 0.151mol),Acetone (9.26g, 0.16mol),Acetic acid (2 mL), magnesium sulfate (10.0 g), and sodium triacetoxyborohydride (96.64 g, 0.456 mol) were added to dichloromethane (100 mL). The reaction was carried out at room temperature overnight. The reaction was monitored by TLC for completeness, filtered, and the filtrate was concentrated under reduced pressure to obtain the product (25 g, yield: 95.6%).
References:
Nanjing Yaojie Good Health Biological Technology Co., Ltd.;Wu Yongqian;Wan Zhonghui CN110857293, 2020, A Location in patent:Paragraph 0967; 0969-0971
![3-Isopropylidenecarbazic acid tert-butyl ester](/CAS/GIF/16689-34-2.gif)
16689-34-2
27 suppliers
$200.00/1g
![1-Boc-2-isopropylhydrazine](/CAS/GIF/16689-35-3.gif)
16689-35-3
110 suppliers
$11.00/250mg
![tert-Butyl carbazate](/CAS/GIF/870-46-2.gif)
870-46-2
533 suppliers
$5.00/10g
![1-Boc-2-isopropylhydrazine](/CAS/GIF/16689-35-3.gif)
16689-35-3
110 suppliers
$11.00/250mg
![N-Boc-O-tosyl hydroxylamine](/CAS/GIF/105838-14-0.gif)
105838-14-0
70 suppliers
$50.00/250mg
![Isopropylamine](/CAS/GIF/75-31-0.gif)
75-31-0
410 suppliers
$14.00/25mL
![1-Boc-2-isopropylhydrazine](/CAS/GIF/16689-35-3.gif)
16689-35-3
110 suppliers
$11.00/250mg
![Di-tert-butyl dicarbonate](/CAS/GIF/24424-99-5.gif)
24424-99-5
824 suppliers
$13.50/25G
![1-Boc-2-isopropylhydrazine](/CAS/GIF/16689-35-3.gif)
16689-35-3
110 suppliers
$11.00/250mg