1-BOC-4-(4-FORMYLPHENYL)PIPERIDINE synthesis

9synthesis methods

Product Name:1-BOC-4-(4-FORMYLPHENYL)PIPERIDINE
CAS Number:732275-93-3
Molecular formula:C17H23NO3
Molecular Weight:289.37

109384-19-2 Synthesis

109384-19-2
469 suppliers
$5.00/1g

732275-93-3
19 suppliers
inquiry

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: 83 percent / iodine; triphenylphosphine; imidazole / tetrahydrofuran / 2 - 20 °C
2.1: zinc; chlorotrimethylsilane; 1,2-dibromoethane / CelPure P₆₅ / N,N-dimethyl-acetamide / 0.5 h
2.2: 99 percent Chromat_. / Cl₂Pd[1,1'-bis(diphenylphosphino)ferrocene]-CH₂Cl₂ complex; copper(I) iodide / N,N-dimethyl-acetamide / 80 °C

References:

Corley, Edward G.;Conrad, Karen;Murry, Jerry A.;Savarin, Cecile;Holko, Justin;Boice, Genevieve [Journal of Organic Chemistry,2004,vol. 69,# 15,p. 5120 - 5123]