1-Boc-5-aminoindole synthesis
- Product Name:1-Boc-5-aminoindole
- CAS Number:166104-20-7
- Molecular formula:C13H16N2O2
- Molecular Weight:232.28
166104-19-4
75 suppliers
$30.00/100mg
166104-20-7
135 suppliers
$13.00/100mg
Yield:166104-20-7 100%
Reaction Conditions:
with palladium 10% on activated carbon;hydrogen in ethyl acetate at 20;
Steps:
2.2 Step 2) tert-butyl 5-aminoindol-1-carboxylate
To a solution of tert-butyl 5-nitro-1H-indole-1-carboxylate (525 mg, 2.0 mmol) in ethyl acetate (8 ml) was added 10% palladium on carbon (50 mg). Stir overnight at room temperature in a hydrogen atmosphere. Suction filteration, The filtrate was evaporated under reduced pressure to give a white solid (469 mg, 100%)
References:
Guangdong Dongyangguang Pharmaceutical Co., Ltd.;Wen Liang;Zheng Jinfu;Zhang Jin;Wu Shoutao;Yuan Xiaofeng;Lin Runfeng;Wang Xiaojun;Zuo Yinglin;Zhang Yingjun CN104311541, 2017, B Location in patent:Paragraph 0164; 0165
24424-99-5
841 suppliers
$13.50/25G
166104-20-7
135 suppliers
$13.00/100mg
6146-52-7
471 suppliers
$13.00/1g
166104-20-7
135 suppliers
$13.00/100mg