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ChemicalBook CAS DataBase List 1-(but-3-yn-1-yl)piperazine
911398-04-4

1-(but-3-yn-1-yl)piperazine synthesis

3synthesis methods
tert-butyl 4-(but-3-yn-1-yl)piperazine-1-carboxylate

1232152-74-7
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1-(but-3-yn-1-yl)piperazine

911398-04-4
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Yield:911398-04-4 95%

Reaction Conditions:

with trifluoroacetic acid in dichloromethane;

References:

Trabocchi, Andrea;Menchi, Gloria;Cini, Nicoletta;Bianchini, Francesca;Raspanti, Silvia;Bottoncetti, Anna;Pupi, Alberto;Calorini, Lido;Guarna, Antonio [Journal of Medicinal Chemistry,2010,vol. 53,# 19,p. 7119 - 7128] Location in patent:supporting information; experimental part