1-Chloro-2,3,3,4,4,5,5-heptafluorocyclopent-1-ene synthesis

Yield:1759-63-3 78.8 %Spectr.

Reaction Conditions:

with potassium fluoride in N,N-dimethyl-formamide at 110; for 6 h;

Steps:

Synthesis of F7-1

General procedure: KF 3.49 g (0.06 mol) and 20.0mL of DMF were placed into a 50 mL, three-necked, round-bottomed flask equipped with a thermometer and an agitating device. The flask was dipped in the oil bath and heated to a different temperature. Then F6-14, F6-13 or F6-12 of 7.32 g (0.03 mol) was added by drops into the above solution. Under magnetic stirring for 6 h, the products’ temperature dropped to room temperature, and they were scrubbed with 100 mL H₂O to remove KF, KCl and DMF and dried with 4 ? molecular sieve to obtain the organic phase of the product. The organic phase of the product was detected by ¹⁹F NMR.

References:

Zhang, Chengping;Qing, Feiyao;Quan, Hengdao;Sekiya, Akira [Journal of Fluorine Chemistry,2016,vol. 181,p. 11 - 16]