1-CHLORO-4-(4-METHYLPHENYL)PHTHALAZINE synthesis
- Product Name:1-CHLORO-4-(4-METHYLPHENYL)PHTHALAZINE
- CAS Number:76972-35-5
- Molecular formula:C15H11ClN2
- Molecular Weight:254.71
51334-85-1
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$125.00/25g
76972-35-5
19 suppliers
$38.53/250mg
Yield:76972-35-5 81%
Reaction Conditions:
with trichlorophosphate for 5 h;Heating;
Steps:
1-Chloro-4-p-tolylphthalazine (6):
In a 100 mL round-bottomedflask compound 2a (1 g) was heated with POCl3 (10 mL) on a boilingwater bath for 5 h. The cooled reaction mixture was poured into ice/cold water, and then extracted with diethyl ether. Evaporation of diethylether under vacuum gave a solid product that was recrystallised to givecompound 6: Yellow crystals; yield 81%;
References:
Hemdan, Magdy M.;Taha, Sherif M.;Gabr, Adel M.;Elkady, Mohamed Y. [Journal of Chemical Research,2014,vol. 38,# 10,p. 617 - 621]
85-55-2
113 suppliers
$10.00/5g
76972-35-5
19 suppliers
$38.53/250mg
1875-48-5
144 suppliers
$17.67/1gm:
76972-35-5
19 suppliers
$38.53/250mg
108-88-3
7 suppliers
$16.10/100ml
76972-35-5
19 suppliers
$38.53/250mg