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ChemicalBook CAS DataBase List 1-CHLORO-4-(4-PYRIDINYLMETHYL)PHTHALAZINE
101094-85-3

1-CHLORO-4-(4-PYRIDINYLMETHYL)PHTHALAZINE synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 4 steps
1: sodium tetrahydroborate / tetrahydrofuran; methanol / 3 h / 20 °C
2: sodium methylate / methanol; Ethyl propionate / 1 h / Reflux
3: hydrazine hydrate / 5 h / 100 °C
4: trichlorophosphate / acetonitrile / 3 h / 90 °C

References:

Zhang, Shu Lan;Liu, Ya Jing;Zhao, Yan Fang;Guo, Qiu Ting;Gong, Ping [Chinese Chemical Letters,2010,vol. 21,# 9,p. 1071 - 1074]