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1-Cycloocten-5-yne, (Z)- synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: bromine / dichloromethane / 0.83 h / 20 °C / 760.05 Torr
2: potassium tert-butylate / 3.33 h / 0 - 40 °C / 760.05 Torr

References:

Gunawardene, Praveen N.;Luo, Wilson;Polgar, Alexander M.;Corrigan, John F.;Workentin, Mark S. [Organic Letters,2019,vol. 21,# 14,p. 5547 - 5551]