1-(Cyclopropylmethyl)-4-nitrobenzene synthesis
6synthesis methods
- Product Name:1-(Cyclopropylmethyl)-4-nitrobenzene
- CAS Number:120383-85-9
- Molecular formula:C10H11NO2
- Molecular Weight:177.2
Yield:-
Steps:
Multi-step reaction with 2 steps
1.1: hydrazine hydrazine hydrate; potassium hydroxide / ethylene glycol / 120 °C / Inert atmosphere
2.1: acetic anhydride; HNO3 / 0.08 h / -42 °C / Inert atmosphere
2.2: 1.5 h / -42 - 20 °C / Inert atmosphere
References:
Calow, Adam D. J.;Dailler, David;Bower, John F. [Journal of the American Chemical Society,2022,vol. 144,# 25,p. 11069 - 11074]