Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

1-(cyclopropylmethyl)piperidin-4-one synthesis

3synthesis methods
-

Yield:49682-96-4 67%

Reaction Conditions:

Stage #1: piperidine-4,4-diol hydrochloridewith sodium carbonate
Stage #2: cyclopropylcarbinyl bromide in acetonitrile at 65;

References:

Faul, Margaret M.;Grutsch, John L.;Kobierski, Michael E.;Kopach, Michael E.;Krumrich, Christine A.;Staszak, Michael A.;Udodong, Uko;Vicenzi, Jeffrey T.;Sullivan, Kevin A. [Tetrahedron,2003,vol. 59,# 36,p. 7215 - 7229]