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90037-19-7

1-Ethyl-3-hydroxypyridin-2(1H)-one synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: potasium hydroxide / propan-1-ol
2: 65 percent / boron tribromide / CH2Cl2 / 24 h / -70 - 20 °C

References:

Ellis, Beverley L.;Duhme, Anne K.;Hider, Robert C.;Hossain, M. Bilayet;Rizvi, Safia;Van Der Helm, Dick [Journal of Medicinal Chemistry,1996,vol. 39,# 19,p. 3659 - 3670]