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ChemicalBook CAS DataBase List 1-(HydroxyMethyl)-cyclopentanecarboxylic acid

1-(HydroxyMethyl)-cyclopentanecarboxylic acid synthesis

3synthesis methods
7,9-Dioxaspiro[4.5]decane-6,10-dione, 8,8-dimethyl-

84449-10-5
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1-(HydroxyMethyl)-cyclopentanecarboxylic acid

102539-92-4
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Yield:102539-92-4 81%

Reaction Conditions:

with samarium diiodide;water in tetrahydrofuran at 20;Inert atmosphere;

References:

Guazzelli, Giuditta;Grazia, Sara De;Collins, Karl D.;Matsubara, Hiroshi;Spain, Malcolm;Procter, David J. [Journal of the American Chemical Society,2009,vol. 131,p. 7214 - 7215] Location in patent:supporting information; experimental part