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ChemicalBook CAS DataBase List 1-ISOPROPYL-2-ACROLEIN-3-(4-FLUOROPHENYL)-INDOLE

1-ISOPROPYL-2-ACROLEIN-3-(4-FLUOROPHENYL)-INDOLE synthesis

5synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: 2,6-di-tert-butyl-pyridine; copper(II) bis(trifluoromethanesulfonate) / dichloromethane / 48 h / 35 °C
2: sodium hydride / N,N-dimethyl-formamide / 3 h / 20 °C
3: trichlorophosphate / acetonitrile / 3 h / 80 °C

References:

Kim, Aejin;Kim, In Su [Bulletin of the Korean Chemical Society,2011,vol. 32,# 10,p. 3748 - 3751]

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