1-isopropyl-3-methyl-1H-pyrazole-5-carboxylic acid synthesis

3synthesis methods

Product Name:1-isopropyl-3-methyl-1H-pyrazole-5-carboxylic acid
CAS Number:50920-68-8
Molecular formula:C8H12N2O2
Molecular Weight:168.19

ethyl 3-methyl-1-(propan-2-yl)-1H-pyrazole-5-carboxylate

50920-67-7
4 suppliers
inquiry

1-isopropyl-3-methyl-1H-pyrazole-5-carboxylic acid

50920-68-8
20 suppliers
$330.00/100mg

Yield:50920-68-8 84%

Reaction Conditions:

with water monomer;lithium hydroxide monohydrate in tetrahydrofuran at 20;

References:

Jeon, Min Jae;Lee, Hyelim;Lee, Jeehee;Baek, Soo Yeon;Lee, Donghee;Jo, Seongman;Lee, Joo-Youn;Kang, Miso;Jung, Hee Ra;Han, Soo Bong;Kim, Nam-Jung;Lee, Sanghee;Kim, Hyejin [Journal of Medicinal Chemistry,2022,vol. 65,# 7,p. 5407 - 5432] Location in patent:supporting information

25016-17-5 Synthesis

5-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER

25016-17-5
143 suppliers
$10.00/250mg

50920-68-8
20 suppliers
$330.00/100mg

References

4027-57-0 Synthesis

Ethyl 3-methyl-1H-pyrazole-5-carboxylate

4027-57-0
246 suppliers
$6.00/1g

50920-68-8
20 suppliers
$330.00/100mg

References