1-METHYL-1H-1,2,3-TRIAZOL-4-AMINE synthesis
- Product Name:1-METHYL-1H-1,2,3-TRIAZOL-4-AMINE
- CAS Number:67545-00-0
- Molecular formula:C3H6N4
- Molecular Weight:98.11
107945-66-4
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Yield: 98%
Reaction Conditions:
with palladium 10% on activated carbon;hydrogen in methanol at 20; for 4 h;
Steps:
293b Example 293b 1-Methyl-1H-1,2,3-triazol-4-amine 293b
Example 293b
1-Methyl-1H-1,2,3-triazol-4-amine 293b
Following the procedure in Example 130b, and starting with 293a (800 mg, 6.25 mmol) and 10% palladium on carbon (50% wet, 160 mg) afforded 293b as a yellow solid (600 mg, 98%).
1H NMR (500 MHz, CDCl3) δ 6.91 (s, 1H), 3.97 (s, 3H), 3.65 (brs, 2H).
References:
F.Hoffmann-La Roche AG;CRAWFORD, James John;ORTWINE, Daniel Fred;WEI, BinQing;YOUNG, Wendy B. EP2773638, 2015, B1 Location in patent:Paragraph 1182; 1184
99848-29-0
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