ChemicalBook CAS DataBase List 1-Methyl-3-Methylene-2-Pyrrolidinone

1-Methyl-3-Methylene-2-Pyrrolidinone synthesis

5synthesis methods

Product Name:1-Methyl-3-Methylene-2-Pyrrolidinone
CAS Number:50586-05-5
Molecular formula:C6H9NO
Molecular Weight:111.14

872-50-4 Synthesis

872-50-4
898 suppliers
$10.00/100ML

50-00-0 Synthesis

50-00-0
850 suppliers
$10.00/25g

50586-05-5
7 suppliers
inquiry

Yield:50586-05-5 60%

Reaction Conditions:

Stage #1: 1-methyl-pyrrolidin-2-onewith sodium hydride;oxalic acid diethyl ester in diethyl ether at 35 - 40; for 72 h;Metallation;Acylation;
Stage #2: formaldehyd in xylene at 100; for 1.5 h;Further stages.;Condensation;

References:

Rigolet, Severinne;Melot, Jean Marie;Vebrel, Joel;Chiaroni, Angele;Riche, Claude [Journal of the Chemical Society. Perkin Transactions 1 (2001),2000,# 7,p. 1095 - 1103]

577780-05-3 Synthesis