![](/CAS/GIF/30668-14-5.gif)
1-MORPHOLINOPROPAN-1-ONE synthesis
- Product Name:1-MORPHOLINOPROPAN-1-ONE
- CAS Number:30668-14-5
- Molecular formula:C7H13NO2
- Molecular Weight:143.18
Yield: 86%
Reaction Conditions:
in chloroformCooling with ice;
Steps:
2.7 4.2.1 1-(1-piperidyl)propan-1-one (A1a)
General procedure: Piperidine (21.73 mL, 0.22 mol) was taken in chloroform (25 mL) and cooled in an ice bath. Propionyl chloride (9.61 mL, 0.11 mol) was added in a drop-wise manner to the above solution of the amine and the mixture was stirred for 30 min. The chloroform layer was initially worked with 10% sodium carbonate solution, then with water and dried over sodium sulfate. After the chloroform layer was retrieved, the pure product obtained was concentrated under reduced pressure.
References:
Joshi, Pranaya V.;Sayed, Alim A.;RaviKumar, Ameeta;Puranik, Vedavati G.;Zinjarde, Smita S. [European Journal of Medicinal Chemistry,2017,vol. 136,p. 246 - 258]
![Morpholine, 4-(1-ethyl-1-propenyl)- (9CI)](/CAS/GIF/13654-48-3.gif)
13654-48-3
3 suppliers
inquiry
![1-MORPHOLINOPROPAN-1-ONE](/CAS/GIF/30668-14-5.gif)
30668-14-5
22 suppliers
$87.79/5g
![Morpholine](/CAS/GIF/110-91-8.gif)
110-91-8
677 suppliers
$9.00/1g
![Propyl propionate](/CAS/GIF/106-36-5.gif)
106-36-5
282 suppliers
$14.00/25mL
![1-MORPHOLINOPROPAN-1-ONE](/CAS/GIF/30668-14-5.gif)
30668-14-5
22 suppliers
$87.79/5g