1-Naphthalenesulfonyl chloride, 2-methyl- synthesis

Yield:-

Reaction Conditions:

with thionyl chloride;N,N-dimethyl-formamide in toluene at 90; for 1 h;

Steps:

D

The title compound from step C (0.46 g) was suspended in toluene (2.2 ml), and SOCl₂ (0.75 ml) and DMF (0.010 ml) were added to the resulting mixture. Heating was then carried out for 1 h at 90° C. until a solution was present. The solution was concentrated completely, and the residue was dried under a high vacuum. The product so obtained was used in the next step without being purified further.

References:

US2008/153843,2008,A1 Location in patent:Page/Page column 82