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ChemicalBook CAS DataBase List 1-oxa-6-thia-spiro[2.5]octane-6,6-dioxide

1-oxa-6-thia-spiro[2.5]octane-6,6-dioxide synthesis

3synthesis methods
2H-Thiopyran-4-ol, tetrahydro-4-(nitromethyl)-, 1,1-dioxide

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1-oxa-6-thia-spiro[2.5]octane-6,6-dioxide

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Yield:-

Steps:

Multi-step reaction with 2 steps
1: Raney nickel; methanol / Hydrogenation
2: acetic acid; aqueous sodium nitrite

References:

Overberger;Katchman [Journal of the American Chemical Society,1956,vol. 78,p. 1965,1967]