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1-Oxaspiro[2.5]octane-2-carbonitrile, (-)- synthesis

1synthesis methods
-

Yield:500899-64-9 85%

Reaction Conditions:

with sodium hydroxide in tetrahydrofuran at 20 - 30; for 0.416667 h;Darzens condensation;

References:

Jonczyk;Gadaj [Polish Journal of Chemistry,2007,vol. 81,# 9,p. 1595 - 1610]