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ChemicalBook CAS DataBase List 1-PalMitoyl-2-arachidoyllecithin

1-PalMitoyl-2-arachidoyllecithin synthesis

4synthesis methods
-

Yield:35418-58-7 63.5%

Reaction Conditions:

Stage #1: 2-chloroethyl phosphorodichloridate;1-O-palmitoyl-2-arachidonoyl-glycerolwith triethylamine in dichloromethane;phosphorylation;
Stage #2: with water;triethylamine in dichloromethane;Hydrolysis;
Stage #3: trimethylamine in ethanol at 70 - 80; for 72 h;Substitution;

References:

Xia, Jie;Hui, Yong-Zheng [Chemical and Pharmaceutical Bulletin,1999,vol. 47,# 11,p. 1659 - 1663]