Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List 1-PENTADECANOL

1-PENTADECANOL synthesis

12synthesis methods
via Myristic acid and the Cyanide (Pentadecanoic nitrile) to the Pentadecanoic acid via Ethylester and reduction to the title alcohol.
-

Yield:629-76-5 89 %Chromat.

Reaction Conditions:

with platinum(IV) oxide;Hoveyda-Grubbs catalyst second generation;hydrogen in dichloromethane at 20; under 2250.23 Torr; for 0.833333 h;Inert atmosphere;Autoclave;

Steps:

Condition A: Tandem cross-metathesis/hydrogenation reaction allyl alcohol with 1-octene
General procedure: The primary alcohols with various chain lengths could be obtained by the reaction of allyl alcohol with a terminal olefin using Hoveyda-Grubbs II and PtO2 catalyst together in one pot. The typical procedure for synthesis of 1-nonanol is as follows: a solution of allyl alcohol (0.5 mmol) and 1-octene (1 mmol) in dichloromethane (2.5 mL) was charged into a 10 mL vial followed by Hoveyda-Grubbs II (0.01 mmol) and PtO2 (0.01 mmol) in under an argon atmosphere, and then the via was placed in a 50 mL stainless autoclave. The autoclave was purged with H2 three times and pressurized by H2 (0.3 MPa), and vigorously stirred at room temperature for 50 min.

References:

Jia, Ruilong;Zuo, Zhijun;Li, Xu;Liu, Lei;Dong, Jinxiang [Chinese Chemical Letters,2020,vol. 31,# 6,p. 1525 - 1529] Location in patent:supporting information

FullText

1-PENTADECANOL Related Search: