1-Phenyl-3-(pyrrolidin-3-yl)urea synthesis

Yield:-

Steps:

Multi-step reaction with 2 steps
1: tetrahydrofuran / 20 °C
2: trifluoroacetic acid / dichloromethane / 0 °C

References:

Modranka, Jakub;Li, Jiahong;Parchina, Anastasia;Vanmeert, Michiel;Dumbre, Shrinivas;Salman, Mayla;Myllykallio, Hannu;Becker, Hubert F.;Vanhoutte, Roeland;Margamuljana, Lia;Nguyen, Hoai;Abu El-Asrar, Rania;Rozenski, Jef;Herdewijn, Piet;De Jonghe, Steven;Lescrinier, Eveline [ChemMedChem,2019,vol. 14,# 6,p. 645 - 662]