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1-Phenyl-5-aminotetrazole synthesis

6synthesis methods
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Yield:5855-52-7 98%

Reaction Conditions:

Stage #1: 4-chloro-2-phenylquinolinewith phenol at 180; for 1 h;
Stage #2: with ammonia at 180; for 5 h;
Stage #3: with sodium hydroxide in water at 20;

References:

Kakadiya, Rajesh;Dong, Huajin;Kumar, Amit;Narsinh, Dodia;Zhang, Xiuguo;Chou, Ting-Chao;Lee, Te-Chang;Shah, Anamik;Su, Tsann-Long [Bioorganic and Medicinal Chemistry,2010,vol. 18,# 6,p. 2285 - 2299] Location in patent:supporting information; experimental part