1-Phenyl-7-(trifluoroMethyl)azepan-2-one synthesis

1synthesis methods

Product Name:1-Phenyl-7-(trifluoroMethyl)azepan-2-one
CAS Number:1224599-71-6
Molecular formula:C13H14F3NO
Molecular Weight:257.25

Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

1000210-73-0
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1-Phenyl-7-(trifluoroMethyl)azepan-2-one

1224599-71-6
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Yield: 87%

Reaction Conditions:

with sodium hydride in tetrahydrofuran at 20; for 2 h;Inert atmosphere;

References:

Wan, Wen;Hou, Jie;Jiang, Haizhen;Yuan, Zongqian;Goubin, Ma.;Zhao, Gang;Hao, Jian [European Journal of Organic Chemistry,2010,# 9,p. 1778 - 1786] Location in patent:experimental part