![](/CAS/GIF/1589-60-2.gif)
1-PHENYLCYCLOHEXANOL synthesis
- Product Name:1-PHENYLCYCLOHEXANOL
- CAS Number:1589-60-2
- Molecular formula:C12H16O
- Molecular Weight:176.25
![Bromobenzene](/CAS/GIF/108-86-1.gif)
108-86-1
496 suppliers
$10.00/5g
![Cyclohexanone](/CAS/GIF/108-94-1.gif)
108-94-1
530 suppliers
$12.00/50g
![1-PHENYLCYCLOHEXANOL](/CAS/GIF/1589-60-2.gif)
1589-60-2
103 suppliers
$47.67/10g
Yield:1589-60-2 97%
Reaction Conditions:
Stage #1: bromobenzenewith magnesium in diethyl ether at 35;
Stage #2: cyclohexanone in diethyl ether at 35; for 5 h;
Steps:
1.a a. Preparation of 1-phenylcyclohexanol.
Add bromobenzene (50g, .31mol), magnesium bar (8.13g, 0.33mol) in a 1000mL three-necked flask and dissolve in an appropriate amount 6 In the ether, it is triggered at 35°C. After the reaction is complete, add cyclohexanone (34.38g, 0.35mol), and react at 35°C. After 5 hours, TLC monitors the progress of the reaction. After the reaction is complete, add the reaction solution to a saturated aqueous solution of ammonium chloride, and use ether After extraction, the extract is dried and evaporated under reduced pressure to obtain the product. The yield is 97.0%.
References:
CN112939864,2021,A Location in patent:Paragraph 0050-0052
![Iodobenzene](/CAS/GIF/591-50-4.gif)
591-50-4
472 suppliers
$10.00/1g
![Cyclohexanone](/CAS/GIF/108-94-1.gif)
108-94-1
530 suppliers
$12.00/50g
![1-PHENYLCYCLOHEXANOL](/CAS/GIF/1589-60-2.gif)
1589-60-2
103 suppliers
$47.67/10g
![Cyclohexanone](/CAS/GIF/108-94-1.gif)
108-94-1
530 suppliers
$12.00/50g
![PHENYLMAGNESIUM BROMIDE](/CAS/GIF/100-58-3.gif)
100-58-3
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$18.00/10ml
![1-PHENYLCYCLOHEXANOL](/CAS/GIF/1589-60-2.gif)
1589-60-2
103 suppliers
$47.67/10g
![Cyclohexylbenzene](/CAS/GIF/827-52-1.gif)
827-52-1
298 suppliers
$5.00/10g
![1-PHENYLCYCLOHEXANOL](/CAS/GIF/1589-60-2.gif)
1589-60-2
103 suppliers
$47.67/10g
![1-Phenyl-1-cyclohexene](/CAS/GIF/771-98-2.gif)
771-98-2
141 suppliers
$10.00/1g
![5-BENZOYLPENTANOIC ACID](/CAS/GIF/4144-62-1.gif)
4144-62-1
74 suppliers
$17.67/1gm:
![2,4,6-Triphenylboroxin](/CAS/GIF/3262-89-3.gif)
3262-89-3
96 suppliers
$6.00/1g
![Cyclohexanone](/CAS/GIF/108-94-1.gif)
108-94-1
530 suppliers
$12.00/50g
![1-PHENYLCYCLOHEXANOL](/CAS/GIF/1589-60-2.gif)
1589-60-2
103 suppliers
$47.67/10g