ChemicalBook CAS DataBase List 1-Propanesulfonic acid

1-Propanesulfonic acid synthesis

12synthesis methods

Product Name:1-Propanesulfonic acid
CAS Number:5284-66-2
Molecular formula:C3H8O3S
Molecular Weight:124.16

107-03-9
216 suppliers
$14.00/25mL

5284-66-2
97 suppliers
$76.00/1g

Yield: 47%

Reaction Conditions:

with hydrogen iodide;dimethyl sulfoxide in water

Steps:

1 Example 1
Example 1 n-Propanethiol (0.52 g; 6.8 mmole), dimethyl sulfoxide (0.1 ml; 1.5 mmole), hydrogen iodide (0.02 ml of a 47 wt.% aqueous solution; 0.13 mmole) and water (10 ml) were charged into a glass pressure reactor. The reactor was closed, pressurized with air to about 100 psig, and heated to 110°C. The reactor pressure at this temperature was about 150 psig. The reactor was kept at the same temperature for 24 hours while the contents were stirred, after which time the reactor was cooled and slowly depressurized. The contents of the reactor were extracted with 25 ml of water. In this manner 0.4 g (47% yield) of n-propane sulfonic acid was produced as determined by titration of the aqueous fraction by 0.1 Normal aqueous sodium hydroxide.

References:

ATOCHEM NORTH AMERICA, INC. EP424616, 1991, A2