![](/CAS/20180703/GIF/1311315-20-4.gif)
1-(Trifluoromethyl)cyclohexanamine hydrochloride synthesis
- Product Name:1-(Trifluoromethyl)cyclohexanamine hydrochloride
- CAS Number:1311315-20-4
- Molecular formula:C7H13ClF3N
- Molecular Weight:203.63
![N-Menzyl-1-(trifluoromethyl)cyclohexan-1-amine](/CAS/20210111/GIF/1100246-29-4.gif)
1100246-29-4
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![1-(Trifluoromethyl)cyclohexanamine hydrochloride](/CAS/20180703/GIF/1311315-20-4.gif)
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Yield:1311315-20-4 91%
Reaction Conditions:
Stage #1: N-benzyl-1-(trifluoromethyl)cyclohexanaminewith formic acid;10% Pd/C;hydrogen in methanol at 45; for 12 h;
Stage #2: with hydrogenchloride in diethyl ether;Inert atmosphere;
References:
Sch?fer, Gabriel;Matthey, Coraline;Bode, Jeffrey W. [Angewandte Chemie - International Edition,2012,vol. 51,# 36,p. 9173 - 9175] Location in patent:supporting information
![Benzenemethanamine, N-cyclohexylidene-](/CAS/20210305/GIF/4471-09-4.gif)
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![Cyclohexanone](/CAS/GIF/108-94-1.gif)
108-94-1
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$12.00/50g
![1-(Trifluoromethyl)cyclohexanamine hydrochloride](/CAS/20180703/GIF/1311315-20-4.gif)
1311315-20-4
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