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10-(3-BroMopropyl)-10H-phenothiazine synthesis

3synthesis methods
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Yield:92357-95-4 65%

Reaction Conditions:

Stage #1: 10H-phenothiazinewith sodium hydride in N,N-dimethyl-formamide;mineral oil at 20; for 4 h;
Stage #2: 1,3-dibromo-propane in N,N-dimethyl-formamide;mineral oil at 0; for 3 h;

References:

Liang, Lijuan;Liu, Chang;Jiao, Xiaojie;Zhao, Liancheng;Zeng, Xianshun [Chemical Communications,2016,vol. 52,# 51,p. 7982 - 7985] Location in patent:supporting information