ChemicalBook CAS DataBase List 5-((6-(2,4-bis(TrifluoroMethyl)phenyl)pyridazin-3-yl)Methyl)-2-(2-fluorophenyl)-5H-iMidazo[4,5-c]pyridine

5-((6-(2,4-bis(TrifluoroMethyl)phenyl)pyridazin-3-yl)Methyl)-2-(2-fluorophenyl)-5H-iMidazo[4,5-c]pyridine synthesis

4synthesis methods

Product Name:5-((6-(2,4-bis(TrifluoroMethyl)phenyl)pyridazin-3-yl)Methyl)-2-(2-fluorophenyl)-5H-iMidazo[4,5-c]pyridine
CAS Number:1000787-75-6
Molecular formula:C25H14F7N5
Molecular Weight:517.4

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5-((6-(2,4-bis(TrifluoroMethyl)phenyl)pyridazin-3-yl)Methyl)-2-(2-fluorophenyl)-5H-iMidazo[4,5-c]pyridine

1000787-75-6
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: sodium hydroxide / N,N-dimethyl-formamide / 3 h
2: sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,2-dimethoxyethane; water / 72 h / 80 °C

References:

GILEAD SCIENCES, INC.;Delaney, William E.;Link, John O.;Mo, Hongmei;Oldach, David W.;Ray, Adrian S.;Watkins, William J.;Yang, Cheng Yong;Zhong, Weidong US2013/273005, 2013, A1