5'-hydroxy-Spiro[cyclopropane-1,1'-[1H]isoindol]-3'(2'H)-one synthesis

1synthesis methods

Product Name:5'-hydroxy-Spiro[cyclopropane-1,1'-[1H]isoindol]-3'(2'H)-one
CAS Number:1007455-36-8
Molecular formula:C10H9NO2
Molecular Weight:175.18

5'-methoxyspiro[cyclopropane-1,1'-isoindolin]-3'-one

1007455-35-7
11 suppliers
inquiry

5'-hydroxy-Spiro[cyclopropane-1,1'-[1H]isoindol]-3'(2'H)-one

1007455-36-8
10 suppliers
$65.00/10mg

Yield:1007455-36-8 41%

Reaction Conditions:

with boron tribromide in dichloromethane at 0 - 20;

References:

Powers, James J.;Favor, David A.;Rankin, Trent;Sharma, Rashmi;Pandit, Chetan;Jeganathan, Azhwarsamy;Maiti, Samarendra N. [Tetrahedron Letters,2009,vol. 50,# 12,p. 1267 - 1269] Location in patent:supporting information; experimental part