7-(2-Carbomethoxyethyl)-5-(2-chlorophenyl)-thieno-1,4-diazepin-2-one synthesis

7synthesis methods

Product Name:7-(2-Carbomethoxyethyl)-5-(2-chlorophenyl)-thieno-1,4-diazepin-2-one
CAS Number:100827-80-3
Molecular formula:C17H15ClN2O3S
Molecular Weight:362.83

19515-61-8 Synthesis

19515-61-8
11 suppliers
$115.00/500mg

7-(2-Carbomethoxyethyl)-5-(2-chlorophenyl)-thieno-1,4-diazepin-2-one

100827-80-3
12 suppliers
$80.00/2mg

Yield:-

Steps:

Multi-step reaction with 6 steps
1: 74 percent / sulfur, Et₃N / dimethylformamide / 3 h / 60 - 70 °C
2: 30 g / KOH, water / methanol / 2 h / Heating
3: 45 percent / H₂SO₄ / 18 h / Ambient temperature
4: 92 percent / aq. NaHCO₃ / toluene / 1.5 h / 40 - 50 °C
5: 25 g / NH₃ / ethyl acetate / 3 h / Ambient temperature
6: 52 percent / silica gel / toluene / Heating

References:

Bechtel;Weber [Journal of Pharmaceutical Sciences,1985,vol. 74,# 12,p. 1265 - 1269]

2-Thiophenepropanoic acid, 5-[(2-aminoacetyl)amino]-4-(2-chlorobenzoyl)-, methyl ester

100827-81-4
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100827-80-3
12 suppliers
$80.00/2mg

References

40018-25-5 Synthesis

40018-25-5
195 suppliers
$9.00/1g

100827-80-3
12 suppliers
$80.00/2mg

References

2-Thiophenepropanoic acid, 5-amino-4-(2-chlorobenzoyl)-

100827-78-9
0 suppliers
inquiry

100827-80-3
12 suppliers
$80.00/2mg

References

2-Amino-3-(2-chlorobenzoyl)-5-(2-carbomethoxyethyl)thiophene

100827-77-8
13 suppliers
$120.00/5mg

100827-80-3
12 suppliers
$80.00/2mg

References