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(2R,3S,4R)-2-(Hydroxymethyl)pyrrolidine-3,4-diol hydrochloride synthesis

6synthesis methods
4H-1,3-Dioxolo[4,5-c]pyrrole-4-methanol, tetrahydro-2,2-dimethyl-, (3aS,4R,6aR)-

209787-68-8
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(2R,3S,4R)-2-(Hydroxymethyl)pyrrolidine-3,4-diol hydrochloride

100991-93-3
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Yield:100991-93-3 100%

Reaction Conditions:

with hydrogenchloride in methanol at 20; for 0.5 h;

References:

Jeon, Jongho;Lee, Jong Hyup;Kim, Jung-Won;Kim, Young Gyu [Tetrahedron Asymmetry,2007,vol. 18,# 20,p. 2448 - 2453]