2-(2-[4-(3-BENZYLOXY-PHENYLSULFANYL)-2-CHLORO-PHENYL]-ETHYL)-2-FLUORO-MALONIC ACID DIETHYL ESTER synthesis

1synthesis methods

Product Name:2-(2-[4-(3-BENZYLOXY-PHENYLSULFANYL)-2-CHLORO-PHENYL]-ETHYL)-2-FLUORO-MALONIC ACID DIETHYL ESTER
CAS Number:1023648-24-9
Molecular formula:C28H28ClFO5S
Molecular Weight:531.04

1-[(3-Chloro-4-ethenylphenyl)thio]-3-(phenylmethoxy)benzene

1023648-20-5
0 suppliers
inquiry

685-88-1 Synthesis

685-88-1
330 suppliers
$9.00/5g

2-(2-[4-(3-BENZYLOXY-PHENYLSULFANYL)-2-CHLORO-PHENYL]-ETHYL)-2-FLUORO-MALONIC ACID DIETHYL ESTER

1023648-24-9
5 suppliers
inquiry

Yield:1023648-24-9 55%

Reaction Conditions:

Stage #1: fluoromalonic acid diethyl esterwith caesium carbonate in dimethyl sulfoxide at 20; for 0.5 h;
Stage #2: 3-[3-(benzyloxy)phenylthio]-6-vinyl-1-chlorobenzene in dimethyl sulfoxide at 20 - 35;Further stages.;

References:

Chino, Masao;Kiuchi, Masatoshi;Adachi, Kunitomo [Tetrahedron,2008,vol. 64,# 17,p. 3859 - 3866]