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ChemicalBook CAS DataBase List 4-tert-ButyldiMethylsilyloxybenzeneacetic Acid Methyl Ester

4-tert-ButyldiMethylsilyloxybenzeneacetic Acid Methyl Ester synthesis

3synthesis methods
14199-15-6 Synthesis
Methyl 4-hydroxyphenylacetate

14199-15-6
303 suppliers
$7.00/10g

18162-48-6 Synthesis
tert-Butyldimethylsilyl chloride

18162-48-6
668 suppliers
$9.00/5g

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Yield:105460-59-1 100%

Reaction Conditions:

with 1H-imidazole in N,N-dimethyl-formamide at 20; for 12 h;

References:

Georgiades, Savvas N.;Clardy, Jon [Bioorganic and Medicinal Chemistry Letters,2008,vol. 18,# 10,p. 3117 - 3121] Location in patent:supporting information; experimental part