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ChemicalBook CAS DataBase List (1S,2R,5R)-5-(4-chloro-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol
105522-08-5

(1S,2R,5R)-5-(4-chloro-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol synthesis

3synthesis methods
1-((3aS,6aR)-6-(benzyloxyMethyl)-2,2-diMethyl-4,6a-dihydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)-4-chloro-1H-iMidazo[4,5-c]pyridine

105522-07-4
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(1S,2R,5R)-5-(4-chloro-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol

105522-08-5
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Yield:105522-08-5 69%

Reaction Conditions:

with boron trichloride in dichloromethane at -75; for 3.5 h;

References:

Tseng, Christopher K. H.;Marquez, Victor E.;Fuller, Richard W.;Goldstein, Barry M.;Haines, David R.;et al. [Journal of Medicinal Chemistry,1989,vol. 32,# 7,p. 1442 - 1446]