2-(2-((2-((4-(tert-Butyl)benzyl)sulfonyl)acetyl)iMino)-3-hydroxy-2,3-dihydrothiazol-4-yl)acetic acid synthesis

1synthesis methods

Product Name:2-(2-((2-((4-(tert-Butyl)benzyl)sulfonyl)acetyl)iMino)-3-hydroxy-2,3-dihydrothiazol-4-yl)acetic acid
CAS Number:1056651-96-7
Molecular formula:C18H22N2O6S2
Molecular Weight:426.51

4-Thiazoleacetic acid, 2-[[2-[[[4-(1,1-dimethylethyl)phenyl]methyl]sulfonyl]acetyl]imino]-2,3-dihydro-3-hydroxy-, ethyl ester

1056652-17-5
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2-(2-((2-((4-(tert-Butyl)benzyl)sulfonyl)acetyl)iMino)-3-hydroxy-2,3-dihydrothiazol-4-yl)acetic acid

1056651-96-7
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Yield:1056651-96-7 100%

Reaction Conditions:

with sodium hydroxide;water in tetrahydrofuran at 20;

References:

Tegley, Christopher M.;Viswanadhan, Vellarkad N.;Biswas, Kaustav;Frohn, Michael J.;Peterkin, Tanya A.N.;Chang, Catherine;Buerli, Roland W.;Dao, Jennifer H.;Veith, Henrike;Rogers, Norma;Yoder, Sean C.;Biddlecome, Gloria;Tagari, Philip;Allen, Jennifer R.;Hungate, Randall W. [Bioorganic and Medicinal Chemistry Letters,2008,vol. 18,# 14,p. 3925 - 3928] Location in patent:scheme or table