Benzyl (2S,3S)-1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-methyl-1-oxopentan-2-ylcarbamate synthesis

1synthesis methods

Product Name:Benzyl (2S,3S)-1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-methyl-1-oxopentan-2-ylcarbamate
CAS Number:1072442-07-9
Molecular formula:C20H22N4O3
Molecular Weight:366.41

95-14-7 Synthesis

95-14-7
862 suppliers
$6.00/100g

3160-59-6
254 suppliers
$10.00/1g

Benzyl (2S,3S)-1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-methyl-1-oxopentan-2-ylcarbamate

1072442-07-9
6 suppliers
$112.00/50mg

Yield:1072442-07-9 96%

Reaction Conditions:

Stage #1: 1,2,3-Benzotriazolewith thionyl chloride at 20; for 0.333333 h;
Stage #2: N-Cbz-L-Isoleucine at 20;

References:

Nsengiyumva, Olivier;Hamedzadeh, Sadra;McDaniel, James;Macho, Jocelyn;Simpson, Grant;Panda, Siva S.;Ha, Khanh;Lebedyeva, Iryna;Faidallah, Hassan M.;Al-Mohammadi, Manal Metgen;Hall, C. Dennis;Katritzky, Alan R. [Organic and Biomolecular Chemistry,2015,vol. 13,# 15,p. 4399 - 4403] Location in patent:supporting information