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1,4-dihydro-6-Methoxy-Pyrido[2,3-b]pyrazin-3(2H)-one synthesis

3synthesis methods
38533-61-8 Synthesis
2-Chloro-6-methoxy-3-nitropyridine

38533-61-8
301 suppliers
$8.00/5g

1,4-dihydro-6-Methoxy-Pyrido[2,3-b]pyrazin-3(2H)-one

1073633-84-7
8 suppliers
inquiry

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Yield:-

Steps:

Multi-step reaction with 4 steps
1: ammonia / methanol / 18 h / 65 °C
2: hydrogen / palladium on activated charcoal / ethanol / 20 °C / 760.05 Torr
3: potassium carbonate / acetonitrile / 20 °C
4: potassium tert-butylate / tetrahydrofuran / 1.5 - 2 h / 0 - 20 °C

References:

WO2008/128961,2008,A1