Ethanimidoyl chloride, N-(2-chlorophenyl)-2,2,2-trifluoro- synthesis
1synthesis methods
- Product Name:Ethanimidoyl chloride, N-(2-chlorophenyl)-2,2,2-trifluoro-
- CAS Number:1087794-62-4
- Molecular formula:C8H4Cl2F3N
- Molecular Weight:242.03
Yield:1087794-62-4 79%
Reaction Conditions:
Stage #1: trifluoroacetic acidwith Carbon tetrachloride;triethylamine;triphenylphosphine in 1,2-dichloro-ethane at 0; for 0.166667 h;
Stage #2: o-chloroaniline in 1,2-dichloro-ethane;Reflux;
References:
Ielo, Laura;Touqeer, Saad;Roller, Alexander;Langer, Thierry;Holzer, Wolfgang;Pace, Vittorio [Angewandte Chemie - International Edition,2019,vol. 58,# 8,p. 2479 - 2484][Angew. Chem.,2019,vol. 131,# 8,p. 2501 - 2506,6] Location in patent:supporting information