11-TRIDECYN-1-OL synthesis

Yield:96 % de

Reaction Conditions:

with chloro(1,5-cyclooctadiene)(pentamethylcyclopentadiene)ruthenium(II);hydrogen;silver trifluoromethanesulfonate in dichloromethane at 20; under 7500.75 Torr; for 0.5 h;Inert atmosphere;Autoclave;diastereoselective reaction;

References:

Radkowski, Karin;Sundararaju, Basker;Fuerstner, Alois [Angewandte Chemie - International Edition,2013,vol. 52,# 1,p. 355 - 360][Angew. Chem.,2012,vol. 125,# 1,p. 373 - 378,6] Location in patent:supporting information