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5-(chloromethyl)-2-phenyl-1,3-thiazole hydrochloride synthesis

2synthesis methods
859485-91-9 Synthesis
(2-phenylthiazol-5-yl)Methanol

859485-91-9
24 suppliers
$45.00/5mg

5-(chloromethyl)-2-phenyl-1,3-thiazole hydrochloride

110704-38-6
7 suppliers
inquiry

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Yield:110704-38-6 87%

Reaction Conditions:

with thionyl chloride in dichloromethane at 0 - 20;Inert atmosphere;

References:

Ang, Chee Wei;Tan, Lendl;Sykes, Melissa L.;Abugharbiyeh, Neda;Debnath, Anjan;Reid, Janet C.;West, Nicholas P.;Avery, Vicky M.;Cooper, Matthew A.;Blaskovich, Mark A. T. [Journal of Medicinal Chemistry,2020,vol. 63,# 24,p. 15726 - 15751]