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2-(4-Methylphenyl)-1,3-dioxoisoindoline-5-carboxylic acid synthesis

1synthesis methods
-

Yield:110784-06-0 89%

Reaction Conditions:

with acetic acid at 130; for 16 h;Condensation;

References:

Kuo, Gee-Hong;Prouty, Catherine;Murray, William V.;Pulito, Virginia;Jolliffe, Linda;Cheung, Peter;Varga, Sally;Evangelisto, Mary;Wang, Jian [Journal of Medicinal Chemistry,2000,vol. 43,# 11,p. 2183 - 2195]