Phosphonous diamide, P-(2-methoxyphenyl)-N,N,N',N'-tetramethyl- synthesis
1synthesis methods
- Product Name:Phosphonous diamide, P-(2-methoxyphenyl)-N,N,N',N'-tetramethyl-
- CAS Number:110904-84-2
- Molecular formula:C11H19N2OP
- Molecular Weight:226.26
Yield:110904-84-2 58%
Reaction Conditions:
Stage #1: 2-bromoanisolewith n-butyllithium in diethyl ether at -78; for 0.5 h;
Stage #2: bis(N,N-dimethylamino)chlorophosphine in diethyl ether at 20 - 22;
References:
Xu, Yingjian;Alcock, Nat W.;Clarkson, Guy J.;Docherty, Gordon;Woodward, Gary;Wills, Martin [Organic Letters,2004,vol. 6,# 22,p. 4105 - 4107]